Research Articles
Microfluidic Platforms for Modeling Vascular Inflammation: A Comprehensive Guide to TEER Measurements and Applications
This article provides researchers, scientists, and drug development professionals with a comprehensive overview of microfluidic platforms for modeling vascular inflammation, with a focus on Transendothelial Electrical Resistance (TEER) as a...
Generating Functionally Active Adipose Tissue-Resident Macrophages Using 3D Culture Systems: A Protocol and Review
This article provides a comprehensive resource for researchers and drug development professionals on the generation and application of functionally active adipose tissue-resident macrophages using advanced 3D culture systems.
A Comprehensive Guide to MiXCR: Mastering Immune Repertoire Analysis for Research and Drug Development
This article provides a comprehensive guide to MiXCR, a powerful computational tool for immune repertoire analysis.
In Silico Mechanistic Modeling of the Immune Response to Burn Injuries: From Cellular Dynamics to Clinical Translation
This article provides a comprehensive overview of in silico mechanistic modeling approaches for deciphering the complex immune response following burn injuries.
Bayesian Optimization in Antibody Design: A New Frontier for Accelerated Therapeutic Discovery
This article explores the transformative role of Bayesian optimization (BO) in computational antibody design, a field critical for developing new biologics.
Multi-Organ-on-a-Chip Systems: A New Paradigm for Immunotoxicity Assessment in Drug Development
This article explores the transformative role of multi-organ-on-a-chip (MOC) systems in advancing immunotoxicity studies.
Decoding Thymic Involution: A Single-Cell RNA Sequencing Atlas of Aging Dynamics
This comprehensive review synthesizes recent advances in single-cell RNA sequencing (scRNA-seq) that are revolutionizing our understanding of thymus aging.
Decoding TCR-pMHC Interactions: From Fundamental Principles to Therapeutic Applications in Adaptive Immunity
This article provides a comprehensive examination of T-cell receptor (TCR) and peptide-major histocompatibility complex (pMHC) interactions, the cornerstone of adaptive cellular immunity.
Decoding Tissue Immunity: Insights from Human Postmortem Studies
This article synthesizes recent advances in our understanding of tissue-specific immune responses, with a particular focus on insights gained from human postmortem studies.
Decoding Immune Variation: How Genetics and Environment Shape Human Health and Disease Treatment
This article provides a comprehensive analysis for researchers and drug development professionals on the complex interplay between genetic susceptibility and environmental factors in shaping inter-individual immune variation.