Research Articles
Mastering the MiXCR 10x-sc-xcr-vdj Preset: A Comprehensive Guide for Immune Repertoire Analysis
This article provides a detailed guide for researchers and drug development professionals on leveraging the MiXCR `analyze` command's `10x-sc-xcr-vdj` preset for single-cell V(D)J and paired Transcriptome analysis of 10x Genomics...
MiXCR Analysis Mastery: A Complete Guide from Raw Data to Biological Insights for Immunology Researchers
This comprehensive guide provides researchers and drug development professionals with a detailed overview of the MiXCR computational pipeline for adaptive immune repertoire analysis.
MiXCR Allele Inference: Complete Guide for Immune Receptor Profiling in Research & Drug Development
This comprehensive guide explores MiXCR for immune receptor allele inference from sequencing data, a critical step in adaptive immune receptor repertoire (AIRR) analysis.
Benchmarking Allele Inference: A Comparative Analysis of MiXCR and TIgGER for Adaptive Immune Receptor Repertoire Profiling
This article provides a comprehensive, targeted analysis for researchers and drug development professionals evaluating the accuracy and performance of allele inference tools in immune repertoire sequencing.
The Complete Guide to MiXCR Alignment Reports: From QC Basics to Advanced Interpretation for Biomedical Research
This comprehensive guide empowers researchers, scientists, and drug development professionals to master the interpretation and quality control of MiXCR alignment reports.
Solving MiXCR's Fragmented Data Dilemma: A Guide to Alignment Preset Optimization for Immune Repertoire Analysis
This article addresses a critical challenge in immune repertoire sequencing (Rep-Seq): the misalignment and loss of fragmented sequence data in MiXCR due to suboptimal preset selection.
Solving MiXCR 'No Hits' Errors: A Complete Troubleshooting Guide for Immunogenomics Researchers
This comprehensive guide addresses the critical issue of MiXCR alignment failures returning zero hits.
MiXCR Barcode Errors Explained: Causes, Solutions & Impact on Immune Repertoire Analysis
This article provides a comprehensive guide for researchers and bioinformaticians encountering absent barcode sequence tag pattern errors in MiXCR.
Demystifying MiXCR's Bimodal UMI Distribution: A Complete Guide for Immune Repertoire Analysis
This article provides a comprehensive guide for researchers and bioinformaticians on interpreting the bimodal distribution of Unique Molecular Identifier (UMI) coverage observed in MiXCR output.
MiXCR UMI Error Correction: A Complete Guide to Accurate Immune Repertoire Profiling
This article provides a comprehensive guide to Unique Molecular Identifier (UMI) error correction within the MiXCR pipeline for immune repertoire analysis.