Research Articles
Langerhans Cells in 3D Skin Models: Function, Culture, and Applications in Immunology Research
This article provides a comprehensive guide for researchers and pharmaceutical developers on the critical role and study of Langerhans cells (LCs) within in vitro skin models.
Mastering LISI Score Interpretation: A Complete Guide to Batch Effect Removal for Single-Cell Data Analysis
This comprehensive guide addresses four critical needs for researchers analyzing single-cell data.
A Comprehensive Guide to LIGER Batch Effect Correction: Protocol, Best Practices, and Benchmarking for Multi-Omic Data Integration
This article provides a complete, actionable guide to the LIGER (Linked Inference of Genomic Experimental Relationships) batch effect correction protocol for researchers integrating single-cell or multi-omics datasets.
Measuring Viral Pathogenesis: A Guide to LDH Assays for Quantifying SARS-CoV-2 Variant-Induced Cytotoxicity
This article provides a comprehensive guide for researchers on employing Lactate Dehydrogenase (LDH) release assays to quantify virus-induced cytotoxicity during SARS-CoV-2 variant infection.
A Comprehensive Guide to the KeratinoSens Nrf2-ARE Pathway Assay: Protocol, Optimization & Validation
This detailed guide provides a complete roadmap for the KeratinoSens assay, a key in vitro method for predicting skin sensitization potential via the Nrf2-Keap1 antioxidant pathway.
Targeting the JAK-STAT Pathway: From Mechanistic Insights to Next-Generation Therapeutics for Autoimmune Inflammation
This article provides a comprehensive synthesis of current research and development on the JAK-STAT pathway in autoimmune inflammation.
Clonal Evolution Decoded: A Performance Benchmark of IgPhyML, GCtree, and ClonalTree for B-Cell Lineage Reconstruction
Accurately inferring the clonal evolution and phylogenetic relationships of B-cell receptors (BCRs) is fundamental to immunology, vaccine development, and therapeutic antibody discovery.
IgFold: Fast Antibody Structure Prediction for Next-Generation Therapeutic Discovery
This article provides a comprehensive guide for researchers and drug development professionals on IgFold, a state-of-the-art deep learning method for rapid and accurate antibody structure prediction.
Decoding Immunity: A Comprehensive Guide to Immunoglobulin Class Switching Network Analysis in Research and Therapeutics
This article provides a detailed exploration of Immunoglobulin (Ig) class switching network analysis, a critical methodology for understanding B-cell biology and humoral immunity.
Ensuring Reproducible Research: A Guide to ISO Standards for Biobanking Quality Control
This article provides researchers, scientists, and drug development professionals with a comprehensive guide to the ISO standards governing biobanking quality control.