Research Articles
Benchmarking Allele Inference: A Comparative Analysis of MiXCR and TIgGER for Adaptive Immune Receptor Repertoire Profiling
This article provides a comprehensive, targeted analysis for researchers and drug development professionals evaluating the accuracy and performance of allele inference tools in immune repertoire sequencing.
The Complete Guide to MiXCR Alignment Reports: From QC Basics to Advanced Interpretation for Biomedical Research
This comprehensive guide empowers researchers, scientists, and drug development professionals to master the interpretation and quality control of MiXCR alignment reports.
Solving MiXCR's Fragmented Data Dilemma: A Guide to Alignment Preset Optimization for Immune Repertoire Analysis
This article addresses a critical challenge in immune repertoire sequencing (Rep-Seq): the misalignment and loss of fragmented sequence data in MiXCR due to suboptimal preset selection.
Solving MiXCR 'No Hits' Errors: A Complete Troubleshooting Guide for Immunogenomics Researchers
This comprehensive guide addresses the critical issue of MiXCR alignment failures returning zero hits.
MiXCR Barcode Errors Explained: Causes, Solutions & Impact on Immune Repertoire Analysis
This article provides a comprehensive guide for researchers and bioinformaticians encountering absent barcode sequence tag pattern errors in MiXCR.
Demystifying MiXCR's Bimodal UMI Distribution: A Complete Guide for Immune Repertoire Analysis
This article provides a comprehensive guide for researchers and bioinformaticians on interpreting the bimodal distribution of Unique Molecular Identifier (UMI) coverage observed in MiXCR output.
MiXCR UMI Error Correction: A Complete Guide to Accurate Immune Repertoire Profiling
This article provides a comprehensive guide to Unique Molecular Identifier (UMI) error correction within the MiXCR pipeline for immune repertoire analysis.
Decoding Adaptive Immunity: A Practical Guide to Analyzing CDR3 Hydrophobicity and Charge with MiXCR
This comprehensive guide empowers immunology researchers and therapeutic developers to extract and interpret critical physicochemical properties of T-cell and B-cell receptor repertoires using MiXCR.
Decoding Antibody Evolution: A Comprehensive Guide to B Cell SHM Tree Analysis with MiXCR
This article provides a detailed guide for researchers, scientists, and drug development professionals on analyzing B cell somatic hypermutation (SHM) lineage trees using MiXCR.
Validating B Cell Hypermutation Analysis with MiXCR: A Comprehensive Guide for Researchers in Immunology and Drug Development
This article provides a detailed guide to validating B cell receptor (BCR) somatic hypermutation (SHM) detection using the MiXCR software suite.