Research Articles
Molecular Pixelation (MPX): Revolutionizing Spatial Proteomics with DNA Pixels for Drug Discovery
This comprehensive guide explores Molecular Pixelation (MPX), a cutting-edge spatial proteomics technology that uses DNA-tagged antibodies ('DNA pixels') to map protein organization on single cells.
MixTCRpred: A Comprehensive Guide to Predicting TCR-Epitope Interactions for Researchers
This article provides a detailed exploration of MixTCRpred, a computational tool for predicting T-cell receptor (TCR) and epitope interactions.
MiXCR vs. Traditional Immune Repertoire Analysis: A Comprehensive Guide for Biomedical Researchers
This article provides researchers, scientists, and drug development professionals with a detailed comparison of the MiXCR bioinformatics toolkit against traditional immune repertoire analysis methods.
Beyond Mouse and Man: A Comprehensive Guide to Analyzing Non-Model Species Immune Repertoires with MiXCR
This article provides a detailed guide for researchers analyzing T- and B-cell receptor repertoires in non-model species using MiXCR.
Optimizing Immune Repertoire Analysis: A Comprehensive Guide to Adjusting MiXCR's Spurious Barcode Filtering Threshold
This guide provides a detailed, step-by-step framework for researchers and drug development professionals to understand, adjust, and validate MiXCR's spurious barcode (PCR/sequencing error) filtering threshold.
MiXCR for Beginners: Your Complete Step-by-Step Guide to Immune Repertoire Analysis
This comprehensive beginner's guide to MiXCR, the industry-standard software for analyzing T- and B-cell receptor sequencing data, provides researchers with everything they need to get started.
Integrating Single-Cell Immune Repertoire Analysis with Bulk RNA-Seq: A Comprehensive MiXCR Workflow Guide for Researchers
This article provides a comprehensive guide for researchers aiming to integrate single-cell T/B cell receptor (TCR/BCR) repertoire analysis, using the MiXCR toolkit, with bulk RNA-sequencing data.
Benchmarking MiXCR: A Guide to Sensitivity and Specificity Analysis Using Simulated Repertoire Data
This article provides a comprehensive guide for researchers and bioinformaticians on evaluating the performance of the MiXCR software for adaptive immune receptor repertoire (AIRR-seq) analysis.
Decoding the Adaptive Immune Repertoire: A Comprehensive Guide to MiXCR V(D)J Segment Analysis for Research and Biomarker Discovery
This article provides a targeted guide for researchers and drug development professionals on analyzing V(D)J gene segment usage with MiXCR.
MiXCR Reproducibility Guide: Solving Inconsistent Results Between Runs for Robust Immune Repertoire Analysis
This comprehensive guide addresses the critical challenge of achieving consistent, reproducible results with MiXCR, a leading tool for adaptive immune receptor repertoire (AIRR) sequencing analysis.